R140G (p.Arg140Gly) variant of STAT6 (P42226)
R140G (p.Arg140Gly) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
R140G (p.Arg140Gly) variant details
- p.Arg140Gly
- ExAC rs771728309
- gnomAD rs771728309
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.18
- CADD 21.00
- PolyPhen-2 0.15
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available