R136S (p.Arg136Ser) variant of STAT6 (P42226)
R136S (p.Arg136Ser) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
R136S (p.Arg136Ser) variant details
- p.Arg136Ser
- ExAC rs779625240
- Missense
- Variant Prioritization Score for Impact Estimate 0.193
- REVEL 0.07
- CADD 23.30
- PolyPhen-2 0.68
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available