P11S (p.Pro11Ser) variant of STAT6 (P42226)
P11S (p.Pro11Ser) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
P11S (p.Pro11Ser) variant details
- p.Pro11Ser
- gnomAD rs1172005597
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.05
- CADD 18.60
- PolyPhen-2 0.01
- SIFT 0.23
- Most common in the South Asian population (allele frequency 5.8e-05)
- Structural context available