L64R (p.Leu64Arg) variant of STAT6 (P42226)
L64R (p.Leu64Arg) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
L64R (p.Leu64Arg) variant details
- p.Leu64Arg
- TOPMed rs909474877
- gnomAD rs909474877
- Missense
- Variant Prioritization Score for Impact Estimate 0.601
- REVEL 0.57
- CADD 25.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available