L64F (p.Leu64Phe) variant of STAT6 (P42226)
L64F (p.Leu64Phe) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
L64F (p.Leu64Phe) variant details
- p.Leu64Phe
- gnomAD rs976116452
- Missense
- Variant Prioritization Score for Impact Estimate 0.559
- REVEL 0.40
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available