L56R (p.Leu56Arg) variant of STAT6 (P42226)
L56R (p.Leu56Arg) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
L56R (p.Leu56Arg) variant details
- p.Leu56Arg
- gnomAD rs1398440820
- Missense
- Variant Prioritization Score for Impact Estimate 0.49
- REVEL 0.38
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available