K153E (p.Lys153Glu) variant of STAT6 (P42226)
K153E (p.Lys153Glu) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
K153E (p.Lys153Glu) variant details
- p.Lys153Glu
- TOPMed rs2034302609
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.07
- CADD 11.80
- PolyPhen-2 0.01
- SIFT 0.65
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available