H25Y (p.His25Tyr) variant of STAT6 (P42226)
H25Y (p.His25Tyr) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
H25Y (p.His25Tyr) variant details
- p.His25Tyr
- ExAC rs773786402
- gnomAD rs773786402
- Missense
- Variant Prioritization Score for Impact Estimate 0.344
- REVEL 0.13
- CADD 23.40
- PolyPhen-2 0.28
- SIFT 0.01
- Most common in the East Asian population (allele frequency 0.00018)
- Structural context available