H163Y (p.His163Tyr) variant of STAT6 (P42226)
H163Y (p.His163Tyr) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
H163Y (p.His163Tyr) variant details
- p.His163Tyr
- ExAC rs774099315
- gnomAD rs774099315
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.05
- CADD 23.20
- PolyPhen-2 0.09
- SIFT 0.03
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available