G5S (p.Gly5Ser) variant of STAT6 (P42226)
G5S (p.Gly5Ser) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G5S (p.Gly5Ser) variant details
- p.Gly5Ser
- ExAC rs750315001
- gnomAD rs750315001
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.15
- CADD 15.90
- PolyPhen-2 0.00
- SIFT 0.96
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available