G5D (p.Gly5Asp) variant of STAT6 (P42226)
G5D (p.Gly5Asp) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
G5D (p.Gly5Asp) variant details
- p.Gly5Asp
- cosmic curated COSV55673
- Missense
- Variant Prioritization Score for Impact Estimate 0.201
- REVEL 0.09
- CADD 16.50
- PolyPhen-2 0.06
- SIFT 0.63
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available