G154R (p.Gly154Arg) variant of STAT6 (P42226)
G154R (p.Gly154Arg) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
G154R (p.Gly154Arg) variant details
- p.Gly154Arg
- Ensembl rs1592571492
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.10
- CADD 10.40
- PolyPhen-2 0.17
- SIFT 0.57
- Most common in the African/African-American population (allele frequency 0.00015)
- Structural context available