G154E (p.Gly154Glu) variant of STAT6 (P42226)
G154E (p.Gly154Glu) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
G154E (p.Gly154Glu) variant details
- p.Gly154Glu
- gnomAD rs915270574
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.22
- CADD 4.47
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available