F41L (p.Phe41Leu) variant of STAT6 (P42226)
F41L (p.Phe41Leu) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
F41L (p.Phe41Leu) variant details
- p.Phe41Leu
- TOPMed rs2034364842
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.11
- CADD 23.40
- PolyPhen-2 0.60
- SIFT 0.46
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available