E149G (p.Glu149Gly) variant of STAT6 (P42226)
E149G (p.Glu149Gly) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
E149G (p.Glu149Gly) variant details
- p.Glu149Gly
- gnomAD rs1465000681
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- REVEL 0.16
- CADD 24.70
- PolyPhen-2 0.45
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available