A157T (p.Ala157Thr) variant of STAT6 (P42226)
A157T (p.Ala157Thr) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A157T (p.Ala157Thr) variant details
- p.Ala157Thr
- gnomAD rs1382133707
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.09
- CADD 12.70
- PolyPhen-2 0.00
- SIFT 0.52
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available