A109T (p.Ala109Thr) variant of STAT6 (P42226)
A109T (p.Ala109Thr) in STAT6 (P42226) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
A109T (p.Ala109Thr) variant details
- p.Ala109Thr
- ExAC rs747992913
- TOPMed rs747992913
- gnomAD rs747992913
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.04
- CADD 23.30
- PolyPhen-2 0.83
- SIFT 0.31
- Most common in the East Asian population (allele frequency 0.00038)
- Structural context available