R197C (p.Arg197Cys) variant of STAT5B (P51692)
R197C (p.Arg197Cys) in STAT5B (P51692) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
R197C (p.Arg197Cys) variant details
- p.Arg197Cys
- gnomAD rs1396130852
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- REVEL 0.38
- CADD 25.30
- PolyPhen-2 0.04
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available