P188A (p.Pro188Ala) variant of STAT5B (P51692)
P188A (p.Pro188Ala) in STAT5B (P51692) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P188A (p.Pro188Ala) variant details
- p.Pro188Ala
- TOPMed rs1324335332
- gnomAD rs1324335332
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.07
- CADD 15.30
- PolyPhen-2 0.01
- SIFT 0.24
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available