M18L (p.Met18Leu) variant of STAT5B (P51692)
M18L (p.Met18Leu) in STAT5B (P51692) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
M18L (p.Met18Leu) variant details
- p.Met18Leu
- gnomAD rs1197447612
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.19
- CADD 22.60
- PolyPhen-2 0.27
- SIFT 0.08
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available