L192P (p.Leu192Pro) variant of STAT5B (P51692)
L192P (p.Leu192Pro) in STAT5B (P51692) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
L192P (p.Leu192Pro) variant details
- p.Leu192Pro
- ExAC rs758519390
- Missense
- Variant Prioritization Score for Impact Estimate 0.485
- REVEL 0.38
- CADD 24.90
- PolyPhen-2 0.89
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available