L162F (p.Leu162Phe) variant of STAT5B (P51692)
L162F (p.Leu162Phe) in STAT5B (P51692) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
L162F (p.Leu162Phe) variant details
- p.Leu162Phe
- ExAC rs759250756
- gnomAD rs759250756
- Missense
- Variant Prioritization Score for Impact Estimate 0.555
- REVEL 0.47
- CADD 23.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available