K84N (p.Lys84Asn) variant of STAT5B (P51692)
K84N (p.Lys84Asn) in STAT5B (P51692) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
K84N (p.Lys84Asn) variant details
- p.Lys84Asn
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.461
- REVEL 0.27
- CADD 23.90
- PolyPhen-2 0.27
- SIFT 0.03
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available