H25Q (p.His25Gln) variant of STAT5B (P51692)
H25Q (p.His25Gln) in STAT5B (P51692) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
H25Q (p.His25Gln) variant details
- p.His25Gln
- TOPMed rs1463676724
- gnomAD rs1463676724
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.30
- CADD 23.20
- PolyPhen-2 0.98
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available