G80R (p.Gly80Arg) variant of STAT5B (P51692)
G80R (p.Gly80Arg) in STAT5B (P51692) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
G80R (p.Gly80Arg) variant details
- p.Gly80Arg
- ExAC rs747225467
- gnomAD rs747225467
- Missense
- Variant Prioritization Score for Impact Estimate 0.51
- REVEL 0.33
- CADD 24.10
- PolyPhen-2 0.95
- SIFT 0.34
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available