G63S (p.Gly63Ser) variant of STAT5B (P51692)
G63S (p.Gly63Ser) in STAT5B (P51692) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
G63S (p.Gly63Ser) variant details
- p.Gly63Ser
- ExAC rs759481948
- TOPMed rs759481948
- gnomAD rs759481948
- Missense
- Variant Prioritization Score for Impact Estimate 0.366
- REVEL 0.12
- CADD 20.90
- PolyPhen-2 0.05
- SIFT 0.61
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available