A20P (p.Ala20Pro) variant of STAT5B (P51692)
A20P (p.Ala20Pro) in STAT5B (P51692) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
A20P (p.Ala20Pro) variant details
- p.Ala20Pro
- TOPMed rs1187221247
- gnomAD rs1187221247
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.18
- CADD 24.00
- PolyPhen-2 0.53
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available