W43R (p.Trp43Arg) variant of STAT4 (Q14765)
W43R (p.Trp43Arg) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
W43R (p.Trp43Arg) variant details
- p.Trp43Arg
- cosmic curated COSV61830
- gnomAD rs1699503036
- Missense
- Variant Prioritization Score for Impact Estimate 0.795
- REVEL 0.89
- MetaLR 0.71
- MetaSVM 0.57
- CADD 33.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available