V7A (p.Val7Ala) variant of STAT4 (Q14765)
V7A (p.Val7Ala) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
V7A (p.Val7Ala) variant details
- p.Val7Ala
- ExAC rs778760914
- gnomAD rs778760914
- Missense
- Variant Prioritization Score for Impact Estimate 0.46
- REVEL 0.40
- MetaLR 0.15
- MetaSVM -0.77
- CADD 26.20
- PolyPhen-2 0.63
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available