V154M (p.Val154Met) variant of STAT4 (Q14765)
V154M (p.Val154Met) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
V154M (p.Val154Met) variant details
- p.Val154Met
- ExAC rs758720903
- gnomAD rs758720903
- Missense
- Variant Prioritization Score for Impact Estimate 0.396
- REVEL 0.23
- MetaLR 0.31
- MetaSVM -0.60
- CADD 24.60
- PolyPhen-2 0.65
- SIFT 0.03
- Most common in the South Asian population (allele frequency 0.00041)
- Structural context available