S72Y (p.Ser72Tyr) variant of STAT4 (Q14765)
S72Y (p.Ser72Tyr) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
S72Y (p.Ser72Tyr) variant details
- p.Ser72Tyr
- TOPMed rs267599129
- Missense
- Variant Prioritization Score for Impact Estimate 0.463
- REVEL 0.30
- AlphaMissense 0.18
- MetaLR 0.26
- MetaSVM -0.58
- CADD 24.30
- PolyPhen-2 0.98
- Population evidence available
- Structural context available