S137L (p.Ser137Leu) variant of STAT4 (Q14765)
S137L (p.Ser137Leu) in STAT4 (Q14765) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes variant effect predictions and structural context.
S137L (p.Ser137Leu) variant details
- p.Ser137Leu
- cosmic curated COSV10743
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- MetaLR 0.20
- MetaSVM -0.86
- SIFT 0.64
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available