R110K (p.Arg110Lys) variant of STAT4 (Q14765)
R110K (p.Arg110Lys) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
R110K (p.Arg110Lys) variant details
- p.Arg110Lys
- TOPMed rs1287831571
- gnomAD rs1287831571
- Missense
- Variant Prioritization Score for Impact Estimate 0.349
- REVEL 0.14
- MetaLR 0.09
- MetaSVM -1.06
- CADD 16.90
- PolyPhen-2 0.05
- SIFT 0.88
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available