Q132R (p.Gln132Arg) variant of STAT4 (Q14765)
Q132R (p.Gln132Arg) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
Q132R (p.Gln132Arg) variant details
- p.Gln132Arg
- TOPMed rs1286913686
- gnomAD rs1286913686
- Missense
- Variant Prioritization Score for Impact Estimate 0.623
- REVEL 0.59
- MetaLR 0.74
- MetaSVM 0.54
- CADD 23.70
- PolyPhen-2 0.71
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available