P98S (p.Pro98Ser) variant of STAT4 (Q14765)
P98S (p.Pro98Ser) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
P98S (p.Pro98Ser) variant details
- p.Pro98Ser
- cosmic curated COSV10467
- Missense
- Variant Prioritization Score for Impact Estimate 0.753
- REVEL 0.79
- MetaLR 0.61
- MetaSVM 0.26
- CADD 25.60
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available