N49S (p.Asn49Ser) variant of STAT4 (Q14765)
N49S (p.Asn49Ser) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
N49S (p.Asn49Ser) variant details
- p.Asn49Ser
- TOPMed rs1277833779
- gnomAD rs1277833779
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.10
- MetaLR 0.09
- MetaSVM -1.04
- CADD 22.30
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available