N25S (p.Asn25Ser) variant of STAT4 (Q14765)
N25S (p.Asn25Ser) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
N25S (p.Asn25Ser) variant details
- p.Asn25Ser
- gnomAD rs1184514035
- Missense
- Variant Prioritization Score for Impact Estimate 0.268
- REVEL 0.09
- MetaLR 0.05
- MetaSVM -1.02
- CADD 16.10
- PolyPhen-2 0.00
- SIFT 0.94
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available