N120S (p.Asn120Ser) variant of STAT4 (Q14765)
N120S (p.Asn120Ser) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
N120S (p.Asn120Ser) variant details
- p.Asn120Ser
- gnomAD rs1355355814
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.09
- MetaLR 0.04
- MetaSVM -1.06
- CADD 17.30
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available