N107Y (p.Asn107Tyr) variant of STAT4 (Q14765)
N107Y (p.Asn107Tyr) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
N107Y (p.Asn107Tyr) variant details
- p.Asn107Tyr
- gnomAD rs1337434431
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.30
- AlphaMissense 0.09
- MetaLR 0.19
- MetaSVM -0.78
- CADD 24.00
- PolyPhen-2 1.00
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available