M99V (p.Met99Val) variant of STAT4 (Q14765)
M99V (p.Met99Val) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
M99V (p.Met99Val) variant details
- p.Met99Val
- ExAC rs752105122
- gnomAD rs752105122
- Missense
- Variant Prioritization Score for Impact Estimate 0.292
- REVEL 0.14
- MetaLR 0.05
- MetaSVM -1.06
- CADD 16.00
- PolyPhen-2 0.00
- SIFT 0.82
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available