M156T (p.Met156Thr) variant of STAT4 (Q14765)
M156T (p.Met156Thr) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
M156T (p.Met156Thr) variant details
- p.Met156Thr
- ESP rs376677137
- ExAC rs376677137
- TOPMed rs376677137
- gnomAD rs376677137
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.10
- MetaLR 0.18
- MetaSVM -0.89
- CADD 20.30
- PolyPhen-2 0.18
- SIFT 0.40
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available