L56F (p.Leu56Phe) variant of STAT4 (Q14765)
L56F (p.Leu56Phe) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
L56F (p.Leu56Phe) variant details
- p.Leu56Phe
- gnomAD rs1320919269
- Missense
- Variant Prioritization Score for Impact Estimate 0.438
- REVEL 0.29
- MetaLR 0.32
- MetaSVM -0.51
- CADD 27.00
- PolyPhen-2 0.95
- SIFT 0.01
- Population evidence available
- Structural context available