K75E (p.Lys75Glu) variant of STAT4 (Q14765)
K75E (p.Lys75Glu) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
K75E (p.Lys75Glu) variant details
- p.Lys75Glu
- cosmic curated COSV61830
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.15
- MetaLR 0.07
- MetaSVM -1.00
- CADD 21.60
- PolyPhen-2 0.04
- SIFT 0.07
- Population evidence available
- Structural context available