K73E (p.Lys73Glu) variant of STAT4 (Q14765)
K73E (p.Lys73Glu) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
K73E (p.Lys73Glu) variant details
- p.Lys73Glu
- ExAC rs763673195
- gnomAD rs763673195
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.12
- MetaLR 0.07
- MetaSVM -1.02
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available