I80M (p.Ile80Met) variant of STAT4 (Q14765)
I80M (p.Ile80Met) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
I80M (p.Ile80Met) variant details
- p.Ile80Met
- TOPMed rs957846209
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.13
- MetaLR 0.07
- MetaSVM -0.98
- CADD 18.50
- PolyPhen-2 0.28
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available