H95R (p.His95Arg) variant of STAT4 (Q14765)
H95R (p.His95Arg) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
H95R (p.His95Arg) variant details
- p.His95Arg
- TOPMed rs1322131618
- gnomAD rs1322131618
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.14
- MetaLR 0.07
- MetaSVM -1.08
- CADD 20.60
- PolyPhen-2 0.06
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available