G125R (p.Gly125Arg) variant of STAT4 (Q14765)
G125R (p.Gly125Arg) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
G125R (p.Gly125Arg) variant details
- p.Gly125Arg
- TOPMed rs1451770735
- gnomAD rs1451770735
- Missense
- Variant Prioritization Score for Impact Estimate 0.673
- REVEL 0.54
- MetaLR 0.80
- MetaSVM 0.50
- CADD 31.00
- PolyPhen-2 0.99
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available