E158K (p.Glu158Lys) variant of STAT4 (Q14765)
E158K (p.Glu158Lys) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
E158K (p.Glu158Lys) variant details
- p.Glu158Lys
- cosmic curated COSV61828
- Missense
- Variant Prioritization Score for Impact Estimate 0.425
- REVEL 0.23
- MetaLR 0.26
- MetaSVM -0.51
- CADD 24.70
- PolyPhen-2 0.25
- SIFT 0.01
- Population evidence available
- Structural context available