A149G (p.Ala149Gly) variant of STAT4 (Q14765)
A149G (p.Ala149Gly) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
A149G (p.Ala149Gly) variant details
- p.Ala149Gly
- ExAC rs778170459
- TOPMed rs778170459
- gnomAD rs778170459
- Missense
- Variant Prioritization Score for Impact Estimate 0.368
- REVEL 0.15
- MetaLR 0.16
- MetaSVM -0.98
- CADD 22.70
- PolyPhen-2 0.01
- SIFT 0.46
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available