A148P (p.Ala148Pro) variant of STAT4 (Q14765)
A148P (p.Ala148Pro) in STAT4 (Q14765) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
A148P (p.Ala148Pro) variant details
- p.Ala148Pro
- ExAC rs747495835
- gnomAD rs747495835
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.28
- MetaLR 0.16
- MetaSVM -0.95
- CADD 21.70
- PolyPhen-2 0.62
- SIFT 0.13
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available